Risk Stratification

GARFIELD-AF collects data on all components of the CHA2DS2-VASc and HAS-BLED risk stratification schemes to assess the risks of stroke and bleeding retrospectively.

Key Data:

  • GARFIELD-AF has confirmed that CHA2DS2-VASc and HAS-BLED are both predictive of the risk of major outcomes (stroke/systemic embolism, major bleeding and mortality), and may provide value in guiding physicians in clinical decision-making
    • Anticoagulation therapy, received by over 60% of patients in GARFIELD-AF cohorts 1 and 2, was associated with a substantially lower risk (35%) of all-cause death at 2-year follow-up
    • The most common causes of death are not known to be significantly influenced by anticoagulation, which suggests that a more comprehensive approach to the management of AF may be needed to reduce the risk of death

Key Publications:

Related Publications

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16 Jun 21

Global status

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Total patients 57,262
Recruitment Recruitment closed
Study end: 2018

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      To find out more about GARFIELD-AF, please contact the Thrombosis Research Institute

      E: garfield@tri-london.ac.uk
      T: 0203 198 9947